In the continues development and implementation of new scientific cameras with the super-resolution RCM system, the Photometrics Prime 95B™ has been added to the list of camera solutions. The Prime 95B™ is the world’s first back-illuminated Scientific CMOS camera and highlights the high sensitivity and sub-diffraction-limited RCM confocal system. The RCM unit and Prime 95B can be added to any microscope making it a cost-effective solution for researchers who are interested in confocal and/or super-resolution imaging.