Fast and Deep Live Imaging with NL5

Confocal.nl recently announced the newest product in their lineup: NL5. NL5 is an easy-to-use and compact confocal microscope system, a great addition to any microscopy facility. With the modular nature of NL5, it is also possible to easily convert any existing widefield fluorescence microscope into a fast confocal microscope system with high sensitivity and resolution.…

Arivis VisionVR Applications

While the history of Virtual Reality (VR) dates back to the 1800s, it only started to gain traction in 2014. Almost a decade has passed since then, but the use of VR in image analysis is still considered a “niche” application. Some might even perceive VR as a gimmick that will eventually fizzle out with time. However, companies such as…

Invi SPIM: Developmental Cell Publication (2022)

The Invi SPIM was used in a recent publication by researchers at the European Molecular Biology Laboratory in Heidelberg. Video: Time-lapse images of an H2B-GFP;mT embryo developing in 3D-geec from D0 to D2. In addition to imaging of the mouse embryo, the Photomanipulation Module of the Invi SPIM was used for precise laser ablations of…

2022 Publication Featuring Huygens

Huygens deconvolution was featured in a publication in the journal Pharmaceutics. Scientists at the University of New Mexico have recently published their research on Mesoporous Silica Nanoparticle (MSN) trafficking in lysosomes along microtubules. MSNs have promising applications in drug delivery and immunotherapy because of their inorganic and inert nature. They are also highly customisable, provide…

Huygens 21.10 Update (November 2021)

Users of SVI-Huygens under a maintenance contract or Huygens Everywhere are now able to update to the latest version of Huygens. The new version brings several improvements: 1. Object analyser: capability to merge objects interactively and compartmental analysis. 2. MIP renderer: synced MIP rendering of two images at the same time, allowing users to easily…

MuVi SPIM Application: 3D Plant Tissue Segmentation

In an eLife publication, researchers at Heidelberg University unveiled a convolutional neural network, PlantSeg, that is capable of robust segmentation of plant cells. The publication featured live images of Arabidopsis Thaliana roots (5 days post germination) that were acquired using the Luxendo MuVi SPIM microscope. The two-sided illumination capability of the MuVi SPIM was used,…

Arivis Vision4D: Large Image Handling

The ImageCore technology used in Arivis Vision4D allows for fuss-free handling of large image sets. As images do not have to be loaded completely to RAM, even laptops that have relatively less RAM is able to open and perform operations on large datasets. In this case study, we explore the use of Arivis Vision4D in…

New Glass Rendering feature in Arivis Vision4D

The excellent 3D-visualisation capability of Arivis Vision4D is further improved with the addition of the new ‘glass’ rendering option for objects. While similar to the existing ‘Transparency’ rendering feature, it differs in the contrast at the periphery. The new ‘glass’ rendering feature defines the object’s periphery while maintaining transparency, allowing for accentuation of compartments in…